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yjbI [2019-06-27 14:09:58]
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yjbI [2019-06-27 14:09:58]

truncated hemoglobin, NO protection
locus
BSU11560
pI
5.17
mw
14.98 kDa
protein length
132 aa Sequence Blast
gene length
399 bp Sequence Blast
function
protection against NO, thiol redox homeostasis
product
truncated hemoglobin
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.10|Resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)]

    • Gene

    Coordinates
    1,234,510 1,234,908

    The protein

    Catalyzed reaction/ biological activity

  • binds sulfide with high affinity [Pubmed|20102180]

    • Protein family

  • protozoan/cyanobacterial globin family (according to Swiss-Prot)

    • Kinetic information

  • K(D) for hydrogen sulfide = 5.0x10(6) M-1 [Pubmed|20102180]

    • Structure

  • [PDB|1UX8]

    • Expression and Regulation

    Operons

    genes
    [gene|948BD57CC45915C7CDDB8EF168287533FC514B7C|yjbI]-[gene|87124945A1CBF7990856FBEB9EAD25096DAC0868|yjbH]
    description
    [Pubmed|17293416]

    regulatory mechanism

  • [protein|2C6386E9A63F410558D168798D077DF91590F454|Spx]: activation, [pubmed|29271514], in [regulon|2C6386E9A63F410558D168798D077DF91590F454|Spx regulon]

    • regulation

  • induced by cell wall stress ([protein|2C6386E9A63F410558D168798D077DF91590F454|Spx]) [pubmed|29271514]

    • additional information

  • A [protein|search|ncRNA] is predicted between [gene|138DC46C976BAA18893B70DF040BA1BB2FA0A77C|yizD] and [gene|87124945A1CBF7990856FBEB9EAD25096DAC0868|yjbH] [PubMed|20525796]
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    Biological materials

    Mutant

  • MGNA-B155 (yjbI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1154 NBRP B. subtilis, Japan]
  • 1A864 ( ''yjbI''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A864&Search=1A864 BGSC]
  • BKE11560 ([gene|948BD57CC45915C7CDDB8EF168287533FC514B7C|yjbI]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTGACTACTCCTTTAA, downstream forward: _UP4_TCTTGACAAACTATCAGCAT
  • BKK11560 ([gene|948BD57CC45915C7CDDB8EF168287533FC514B7C|yjbI]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTGACTACTCCTTTAA, downstream forward: _UP4_TCTTGACAAACTATCAGCAT

    • References

  • 17293416,19899166,20102180,22759230,26001125,29271514